Congenital Cranial Dysinnervation Disorder: An Unusual Phenotype With Multiple Cranial Neuropathies and Novel Neuroimaging Findings

A congenital cranial dysinnervation disorder: Möbius' syndrome.

Möbius' syndrome, also known as Möbius' sequence, is a nonprogressive cranial dysinnervation disorder characterized by congenital facial and abducens nerve paralysis. Here, we report a 5-day-old girl who was conceived after in vitro fertilization with poor suck and facial paralysis. She had bilaterally ptosis and lateral gaze limitation, left-sided deviation of the tongue, dysmorphic face, hypo...

Orofacial EMG in Congenital Multiple Cranial Neuropathies

Investigators from Armand-Trousseau hospital and University of Paris studied 90 infants aged birth to 6 months with multiple cranial nerve involvement.

Congenital crocodile tears with Duane's syndrome--congenital cranial dysinnervation syndrome.

Multiple cranial neuropathies.

Patients presenting with multiple cranial neuropathies are not uncommon in neurologic clinical practice. The evaluation of these patients can often be overwhelming due to the vast and complicated etiologies as well as the potential for devastating neurologic outcomes. Dysfunction of the cranial nerves can occur anywhere in their course from intrinsic brainstem dysfunction to their peripheral co...

Multiple cranial neuropathies

There are several syndromes of multiple cranial nerve involvement. One syndrome described by Garcin was a step-b-step ipsilateral involvement of all 12 cranial nerves unilaterally. This term is now used for multiple cranial nerve palsies that do not fit into any of the other named syndromes. This article describes the various pathologies associated with multiple cranial nerve palsies and their ...